Inhibitor or Activator Screening Service for Cytoskeleton
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- Inhibitor or Activator Screening Service for Cytoskeleton
The cytoskeleton is an indispensable cellular structure for cellular life activities, and the complex network system it forms is important for cellular morphological changes and maintenance, cell division and differentiation, intracellular material transport, cellular information transfer and gene expression. CD BioSciences offer hundreds of compounds for cytoskeleton research. We actively follow the latest science, so our customers can rely on us to provide the latest types of cytoskeletal inhibitors and activators.
The cytoskeleton is responsible for contraction, cell motility, movement of organelles and vesicles in the cytoplasm, cytoplasmic division, intracellular signaling, and many other functions critical to cellular homeostasis and survival. Abnormal cytoskeletal proteins are the underlying cause of many pathological phenotypes, including several cardiovascular disease syndromes, neurodegeneration, cancer, liver cirrhosis, pulmonary fibrosis, and many others.
We offer a collection of various cytoskeleton-related compounds that focus on key targets in the cytoskeletal signaling pathway and can be used in the study of cytoskeletal signaling pathways and related diseases.
Target | Description | |
---|---|---|
Microtube Associated | ROCK, PI3K, ERK, Akt, Rho, APC, STAT3, PAK, CDK1, RAC1, etc. | Microtubules are important targets for new drug discovery, and antitumor drugs that act on microtubules are an effective class of drugs for clinical application. These drugs inhibit microtubule polymerization, disrupt microtubule dynamic disequilibrium, disrupt the spindle, block the cell cycle, and cause tumor cell death. |
Actin | ARPC2, Rho/MRTF, Arp2/3, etc. | Mutations in the different genes that regulate actin production in humans can cause muscular diseases, variations in the size and function of the heart as well as deafness. The make-up of the cytoskeleton is also related to the pathogenicity of intracellular bacteria and viruses, particularly in the processes related to evading the actions of the immune system. |
Intermediate Filaments | NF-κB, MMP-1, Keratin, ERK1/2, etc. | Intermediate fibers are tissue-specific, and different cell types contain different IF proteins. Tumor cells retain IF from the source cells even after metastasis, so IF antibodies can be used to identify the origin of the tumor. |
CD BioSciences' cytoskeleton compound Library collects hundreds of cytoskeleton-related compounds with action targets including Microtubule/Tubulin, Kinesin, PKC, MAPK, etc., which can be used for pharmacological research and drug development of cytoskeleton signaling pathways and related diseases.
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CD BioSciences has a professional team and advanced equipment, and the whole process is operated by experienced technicians to provide our customers with cytoskeleton-related research service. If you have any needs, please contact us.
For research use only. Not intended for any clinical use.