The cytoskeleton controls the morphological and dynamic characteristics of eukaryotic cells and plays an important role in maintaining cellular integrity. CD BioSciences uses cytoskeletal imaging, labeling and detection research tools and technical resources to save you more time for research and new discoveries. Design and optimize your protocols for high-quality experimental data using powerful assay kits and imaging systems.
The cytoskeleton is often central to the study of cellular health and disease processes because of its ability to act not only as a cellular scaffold but also to participate in organelle transport, cell division, cell motility and signaling. Cytoskeletal dyes are commonly used as benchmark markers for fluorescence imaging of live and fixed cells for cell orientation and co-localization. In addition, various dye-couplers and fluorescent proteins that react with cytoskeletal subclasses are often used in cytoskeletal studies.
Visualization of cortical microtubule networks in plant cells by live imaging and immunostaining [1].
Visualization of structural information about cytoskeletal organization is essential for understanding its function and the mechanisms underlying various forms of cellular activity. A variety of bioimaging platforms are now available to provide researchers with a wide range of cytoskeletal imaging services.
| Technology | Advantages | Application |
|---|---|---|
| Fluorescence Microscope | Low cost, high sensitivity, multi-color imaging, and simple operation. | Laser Confocal Microscopy, In Vivo Imaging System, TIRF, FRET, FRAP |
| Electron Microscope, EM | High resolution for ultrastructural observation. | TEM: sub-microstructural or ultrastructural imaging. Cryo-EM: temperature-sensitive samples imaging. |
| Cryoelectronic Tomography, cryo-ET | High resolution, protein interaction visualization, and dynamic imaging. | The three-dimensional structure of proteins, viruses, organelles, and the complexes formed between them. |
| Atomic Force Microscope, AFM | No sample handling required, 3D structural imaging. | The surface structure imaging of solid materials including insulators. |
| X-ray Diffraction | The most effective and widely used method for structural analysis. | Crystal structure determination |
| Nuclear Magnetic Resonance, NMR | No radiation damage, fast imaging speed, high spatial and temporal resolution, and in vivo imaging. | Biostructure imaging, tumor discovery, etc. |
| Positron Emission Computed Tomography, PET | High sensitivity, high specificity, whole body imaging and high safety. | Diagnosis and differentiation of multiple diseases, efficacy evaluation, organ function research and new drug development. |
CD BioSciences provides the most comprehensive services for cytoskeleton imaging projects. Through strict monitoring and effective execution, we are committed to providing the best value solutions to complete your project.
Advanced Biotechnology
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CD BioSciences has a professional team and advanced equipment, and the whole process is operated by experienced technicians to provide our customers with cytoskeleton-related research service. If you have any needs, please contact us.
For research use only. Not intended for any clinical use.
