Metastasis is the cause of the largest number of cancer deaths. Metastatic disease, or the movement of cancer cells from one site to another, is a complex process that requires significant remodeling of the cytoskeleton. With in-depth knowledge of cytoskeleton-related fields and extensive project experience, CD BioSciences provides reference materials on cytoskeleton and tumors to help customers understand our related testing services and welcomes you to contact us directly for more specific solutions.
Research for Cancer Cell Biomechanics
Cell mechanics is a frontier area of modern biomechanics that has been developing very rapidly in recent years. It involves the study of the deformation, elastic constants, viscoelasticity, adhesion and other mechanical properties of cells, cell membranes and cytoskeleton under load, as well as the influence of mechanical factors on cell growth.
Biomechanical Research Technology
- Microtubule Aspiration Technology
- Atomic Force Microscopy
- Scanning Force Microscopy
- Optical Tweezers & Traps
Biomechanical Research on Cancer Cells
- Cancer Cell Viscoelasticity Research
The infiltrative growth of cancer cells is a complex process based on the movement and deformation of cancer cells. The alteration of viscoelastic properties of cancer cells may have a significant impact on the interaction between tumor cells and their microenvironment and the metastasis of tumor cells. Therefore, it is important to study the viscoelastic properties of cancer cells and to elucidate their role in carcinogenesis, growth, and metastasis.
- Cancer Cell Adhesion Research
In the case of cancer cells, defects in cytoskeletal structure or function are important causes of non-inhibited proliferation of tumor cell contacts. It has been shown that the cytoskeletal system is directly related to cell adhesion, and abnormalities in the cytoskeleton of cancer cells may be the structural basis for their abnormal adhesion.
Initial stages of cancer cell dissemination [1].
- Cancer Cell Traction Assay
The enzymes secreted by cancer cells contain a group of enzymes called matrix metalloproteases (MMPs). These enzymes act as "molecular scissors" to cut off proteins that block the movement of metastatic cancer cells. Once across the basement membrane, cancer cells can metastasize throughout the body in many ways. For example, they can squeeze through the endothelial cells of blood vessels and enter the bloodstream. Once in the bloodstream, these cells float through the circulatory system until they find a suitable place to reside, and then they re-enter the tissue. They begin to grow and proliferate at the new site, forming a new tumor.
Our Services
The biomechanical properties of cancer cells and their surrounding extracellular matrix have been proposed as promising biomarkers for cancer diagnosis and prognosis. CD BioSciences offers researchers a variety of cellular mechanics assays for cancer cells with its highly accurate cellular biomechanics analysis platform.
Cancer Cell Biomechanical Assay
The mechanical properties of cancer cells are also different from those of normal cells due to changes in the physiological properties of the cells. We provide cellular viscoelasticity assay; cellular adhesion assay and cell traction assay for various types of cancer cells to help our clients study the physiological properties of cancer cells in depth and develop cancer diagnostic tools.
Our Advantages
Cost Effective
Customizable
High Quality
High Efficiency
CD BioSciences provides our global customers with cost effective, high quality and efficient research solutions for cytoskeleton related diseases. We guarantee on-time delivery of our products and results, please contact us for more details.
For research use only. Not intended for any clinical use.
