Prior to 1992, microtubule and actin were generally thought too exclusively be eukaryotic. Subsequently, three laboratories independently identified FtsZ as a protein known to be a key player in bacterial cytoplasmic division, and its "microtubule signature sequence" was present in all α-, β- and γ-microtubule. X-ray crystal structures have confirmed that several bacterial proteins are homologs of eukaryotic microtubule and actin.
Different Types of Prokaryotic Cytoskeleton
| FtsZ |
FtsZ (cytosolic GTPase) is a characteristic protein of bacterial cytosolic organs. This protein accumulates early in dividing cells and plays a key role in septum formation in most bacteria and chloroplasts. It is also considered to be the bacterial cytoskeletal counterpart of eukaryotic microtubules. |
| MerB |
Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization maintains elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature. |
| CreS |
CreS has significant structural and biochemical correlation with eukaryotic IF proteins and was the first of this class to be identified; other proteins do not actually share a high degree of structural similarity with IF proteins and may actually exhibit convergent evolution, hence they are also known as coiled-coil-rich proteins, or Ccrps. |
We offer ready-to-use antibodies for prokaryotic cytoskeleton, please visit our product page if you are interested.
Our Services
The cytoskeleton of prokaryotes has been extensively studied, but progress has been slow due to technical limitations and the ultra-microscopic size of prokaryotes. CD BioSciences offers a one-stop customization service for prokaryotic cytoskeletal antibodies, providing high-quality, high-affinity antibodies of different species according to your needs.
- Monoclonal and Polyclonal Antibody Development for Prokaryotic Cytoskeleton
The use of polyclonal and monoclonal antibodies has increased significantly in recent years. Each type of antibody has its own advantages and disadvantages, and we offer efficient antibody production services, so you can choose according to your research needs.
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Monoclonal Antibodies |
Polyclonal Antibodies |
| Preparation Cost |
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* |
| Preparation Speed |
* |
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| Non-specific Antibodies |
* |
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| Recognition Sites |
Single Table Location |
Multiple Table Locations |
| Batch Differences |
* |
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| Stabilization |
* |
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| Advantages |
Commonly used to detect mixed proteins with high specificity. |
Usually preferred for detection of denatured proteins with higher affinity. |
- Model Organism Prokaryotic Cytoskeleton Antibody Development
We develop and produce prokaryotic cytoskeleton antibodies for a wide range of model organisms, providing researchers with antibodies to model organism cytoskeletal targets, including cyanobacteria, E. coli, lactic acid bacteria, etc.
- Prokaryotic Cytoskeleton Antibody Development Services from Different Hosts
Mice and rats are the host species most commonly used to produce research antibodies, especially in the case of monoclonal antibodies. Whereas polyclonal antibodies can be produced in mice or rats, they are usually made in larger animals, such as rabbits, goats, donkeys or sheep, from which it is easier to collect large amounts of serum.
※ There are different subclasses of IgG prepared using different species of animals, and the common subclasses of IgG from different species are as follows.
| Species |
IgG Subclass |
| Rabbit |
IgG (no subclass) |
| Mouse |
IgG1, IgG2a, IgG2b, IgG2c, IgG3 |
| Rat |
IgG1, IgG2a, IgG2b, IgG2c, IgM |
| Goat |
IgG1, IgG2 |
| Caw |
IgG1, IgG2 |
| Horse |
IgGa, IgGb, IgGc, IgG(B), IgG(T) |
| Pig |
IgG1, IgG2a, IgG2b, IgG3, IgG4 |
We provide antibody development services for different hosts (mouse, rat, rabbit, goat, etc.) according to the needs of different customers and are committed to fulfill your experimental needs in all aspects.
Antibody Customization Process
Our Advantages
Advanced Biotechnology
Customizable Designs
Competitive Pricing
Best After-sales Service
CD BioSciences has a professional team and advanced equipment, and the whole process is operated by experienced technicians to provide our customers with cytoskeleton-related research service. If you have any needs, please contact us.
For research use only. Not intended for any clinical use.
