Microtubules play a key role in mitosis, intracellular transport and motility and are a major therapeutic
target for cancer. Also, microtubules are important for intracellular targeted transport of vesicles,
proteins and messenger RNA. Immunohistochemical images show that many key cancer proteins are associated
with microtubules. The specificity of antibodies represents a potential therapeutic advantage and is an
important component of oncology research.
The evolutionarily ancient and highly conserved actin molecules reversibly assemble into filaments that
constitute one of the three major cytoskeletal polymers. Actin is involved in many cellular functions,
including interaction with myosin, intracellular transport, cell structure and motility, muscle contraction,
and cytoplasmic division. In recent years, the use of polyclonal and monoclonal antibodies has greatly
increased, and you can choose according to your research needs.
Intermediate filament (IF) supergene family proteins are prevalent structural components that form the
cytoskeleton in animal tissues in a cell type-specific manner. All IF proteins show a distinctly organized,
extended α-helical conformation prone to form two-stranded coiled coils, which are the basic building blocks
of these highly flexible, stress-resistant cytoskeletal filaments. In recent years, the use of polyclonal
and monoclonal antibodies has greatly increased, and you can choose according to your research needs.
For research use only. Not intended for any clinical use.