Sirt1/2-IN-1

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Sirt1/2-IN-1

Cat. No. CIA-11364

CAS No. 2402779-21-7

Key Features and Details

  • SIRT1 and SIRT2 inhibitor
  • 420.93
  • C22H13ClN2OS2

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Product Overview
Activity SIRT1 and SIRT2 inhibitor
Description Sirt1/2-IN-1 (Compound 7) is a SIRT1 and SIRT2 inhibitor with IC50 values of 1.81, 2.10 and 20.5 µg/mL against SIRT1, SIRT2 and SIRT3, respectively. Sirt1/2-IN-1 displays activity in hyperacetylation of α-tubulin protein with an IC50 of 32.05 µg/mL. Sirt1/2-IN-1 shows prominent anticancer activity.
Product Details
Product Name Sirt1/2-IN-1
CAS. No. 2402779-21-7
Molecular Formula C22H13ClN2OS2
Molecular Weight 420.93
SMILES O=C1CSC2=NC(C3=CC(Cl)=CC=C3S4)=C4C(C5=CC=C6C=CC=CC6=C5)N21
Storage & Handling

For research use only. Not intended for any clinical use.

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