Cat No. CA-11159
Product Size
Online Inquiry| Target Information | |
|---|---|
| Target Name | DES |
| Gene Name | Desmin |
| Gene Abbr. | DES |
| Gene ID | 1674 |
| Synonyms | CMD1I; CSM1; CSM2; DES; DESM_HUMAN; FLJ12025; FLJ39719 |
| Product Details | |
|---|---|
| Product Name | Recombinant Desmin Mouse Monoclonal Antibody |
| Description | Recombinant Desmin Mouse Monoclonal [rDES/1711]Antibody. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | rDES/1711 |
| Isotype | IgG1 |
| Immunogen | Recombinant full-length human desmin protein. |
| Conjugate | Unconjugated |
| Purification | Protein A/G chromatography. |
| Usage | |
|---|---|
| Applications | IHC-P |
| Reactivity | Hu/Mu, Rt, Hm, Chk |
| Specificity | Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain α-helical coiled-coil molecμLes arranged on an imperfect helical laice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adμLt differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles.Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascμLar cells of glomus tumors of the skin. |
| Storage & Handling | |
|---|---|
| Storage | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C. Avoid freeze / thaw cycles. |
| FormuLation | Supplied in 10 mM Phosphate Buffered Saline; without Sodium Azide and Carrier Free. |
| Product Form | Liquid |
| Concentration | 1 mg/mL |
| Disclaimer | This product is for research use only. It is not intended for diagnostic or therapeutic use. |
For research use only. Not intended for any clinical use.