MMAF
Key Features and
Details
- Tubulin polymerization inhibitor
-
731.96
-
C39H65N5O8
Product Overview |
Activity |
Tubulin polymerization inhibitor |
Description |
MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN-CD19A. |
Product Details |
Product Name |
MMAF |
CAS. No. |
745017-94-1 |
Molecular Formula |
C39H65N5O8 |
Purity |
>99% |
Molecular Weight |
731.96 |
SMILES |
CC(C)[C@H](NC)C(N[C@H](C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)C)=O)C(C)C)=O |
For research use only. Not intended for any clinical use.