The cytoskeleton controls the morphological and dynamic characteristics of eukaryotic cells and plays an important role in maintaining cellular integrity. CD BioSciences uses microtubule structure imaging, labeling and detection research tools and technical resources to save you more time for research and new discoveries. Design and optimize your protocols for high-quality experimental data using powerful assay kits and imaging systems.
Microtubule Structure
Microtubules are hollow polymers grown by assembling heterodimers of α- and β-tubulin with a width of about 25 nm and a length ranging from 1 μm to 100 μm. These heterodimeric microtubule subunits are referred to as αβ-microtubule, microtubule dimers or simply "microtubule". Both microtubules and actin filaments have physical properties similar to those of hard plastic plexiglass, but due to their larger diameter and tubular structure, microtubules are much more rigid.
Microtubule structure [1].
Different Microtubule Isomers
| α- and β-microtubule |
α- and β-microtubule proteins assemble into specialized heterodimers to form cytoplasmic microtubules. Both bind nucleotide GTP, but only the β-subunit hydrolyzes its GTP during normal microtubule polymerization. |
| γ-microtubule |
γ-microtubule is a key part of the mechanism that enables nucleation of new microtubule structures. Together with α- and β-microtubule, they form the minimal set of eukaryotic microtubule proteins. |
| δ-, ɛ- and ζ-microtubule |
δ-, ɛ-, and ζ-microtubule isoforms are present in cilia, flagella, and/or matrix, and they are usually specific for organisms with these structures. |
Our Services
CD BioSciences offers services including real-time microtubule localization, 3D structural imaging, and crystal structure analysis by combining powerful automated image acquisition and analysis with the help of our versatile microscopic instruments. Our microscopy systems provide you with intelligent innovations in structural imaging that can help you achieve optimal image quality.
- Multiple High Quality Structural Imaging Systems
- Microtubule Structural Imaging for Different Types of Cells
- Microtubule Structural Imaging in Different Stages of Cell Cycles
- Microtubule Structural Imaging for Different Species
Our Advantages
Advanced Biotechnology
Customizable Designs
Competitive Pricing
Best After-sales Service
CD BioSciences has a professional team and advanced equipment, and the whole process is operated by experienced technicians to provide our customers with cytoskeleton-related research service. If you have any needs, please contact us.
Reference
- Goodson H V, et al. Microtubules and microtubule-associated proteins[J]. Cold Spring Harbor perspectives in biology, 2018, 10(6): a022608.
For research use only. Not intended for any clinical use.
