Cat. No. CIA-11291
CAS No. 22144-77-0
Key Features and Details
Product Size
Online Inquiry| Product Overview | |
|---|---|
| Activity | Actin polymerization inhibitor |
| Description | Potent actin polymerization inhibitor. |
| Product Details | |
|---|---|
| Product Name | Cytochalasin D |
| Chemical Name | (3S, 3aR, 4S, 6S, 6aR, 7E, 10S, 12R, 13E, 15R, 15aR)-15-(Acetyloxy)-3, 3a, 4, 5, 6, 6a, 9, 10, 12, 15-decahydro-6-12-dihydroxy-4, 10, 12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindole-1, 11(2H)-dione |
| PubChem ID | 5458428 |
| CAS. No. | 22144-77-0 |
| Molecular Formula | C30H37NO6 |
| Biological Description | Potent actin polymerization inhibitor. Binds to G- and F-actin. Stimulates actin depolymerization. Induces cell cycle arrest at G1-S. Activates p53-dependent pathways. Cell permeable. |
| Solubility | Soluble in ethanol to 10 mM and in DMSO to 50 mM |
| Purity | >98% |
| Molecular Weight | 507.63 |
| SMILES | CC1CC=CC2C(C(=C)C(C3C2(C(C=CC(C1=O)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)O |
| Source | Zygosporium mansonii |
| Storage & Handling | |
|---|---|
| Storage Instructions | Shipped at 4 °C. Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months. |
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
For research use only. Not intended for any clinical use.