Cat. No. CIA-11273
CAS No. 442633-00-3
Key Features and Details
Product Size
Online Inquiry| Product Overview | |
|---|---|
| Activity | Actin polymerization inhibitor |
| Description | Potent inhibitor of actin polymerization. |
| Product Details | |
|---|---|
| Product Name | CK 666 |
| Chemical Name | 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide |
| PubChem ID | 589075 |
| CAS. No. | 442633-00-3 |
| Molecular Formula | C18H17FN2O |
| Biological Description | Potent inhibitor of actin polymerization. Inhibits the Arp2/3 (IC50 = 17 μM), SpArp2/3 (IC50 = 5 μM) and HsArp2/3 complexes (IC50= 4 μM) by preventing a shift into an active conformation. |
| Solubility | Soluble in DMSO to 100 mM and in ethanol to 100 mM |
| Purity | >96% |
| Molecular Weight | 296.34 |
| SMILES | Fc1ccccc1C(=O)NCCc2c3ccccc3nc2C |
| Source | Synthetic |
| Storage & Handling | |
|---|---|
| Storage Instructions | Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months. |
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
For research use only. Not intended for any clinical use.
