Product Size
50 mg
10 mg
Custom Size
Product Overview
Description
Potent, selective c-Raf inhibitor.
Biological Description
Potent, cell-permeable and selective c-Raf inhibitor (IC50 = 70 nM). Displays 10-fold selectivity over b-Raf. Inhibits carcinoid cell growth. Also inhibits growth and induces apoptosis in pancreatic cancer cells.
Solubility Overview
Soluble in DMSO to 100 mM.
Chemical Properties
Chemical Name
3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methylphenyl]benzamide
Molecular Weight (Da)
389.45
Molecular Formula
C23H23N3O3
SMILES
O=C(Nc2cc(NC(=O)c1cccc(c1)N(C)C)ccc2C)c3ccc(O)cc3
Storage & Handling
Storage Instructions
Store at 4 °C. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
