Product Size
50 mg
10 mg
Custom Size
Product Overview
Description
Selective N-WASP inhibitor.
Biological Description
Selective neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. Binds the GTPase binding domain stabilising the autoinhibited conformation. Prevents activation of Arp2/3 complex in the actin cytoskeleton.
Solubility Overview
Soluble in DMSO to 100 mM.
Chemical Properties
Chemical Name
3,6-Dibromo-α-[(dimethylamino)methyl]-9H-cabazole-9-ethanol
Molecular Weight (Da)
426.15
Molecular Formula
C17H18Br2N2O
SMILES
CN(C)CC(O)Cn3c1ccc(Br)cc1c2cc(Br)ccc23
Storage & Handling
Storage Instructions
Store at 4 °C. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
