Product Overview
Reactivity
Human, Mouse, Rat (predicted: Chicken, Guinea pig, Cow, Dog, Chimpanzee)
Applications
ICC/IF, IHC-P, IP, WB
Target Information
Alternative Names
CTRCT30; Epididymis luminal protein 113; FLJ36605; HEL113; VIM; VIME_HUMAN; Vimentin
Function
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
Tissue Specificity
Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C. Avoid freeze / thaw cycle.
Storage Buffer
79% PBS, 20% Glycerol (glycerin, glycerine). pH: 7.00.
Preservative
0.025% Proclin 300
