Product Overview
Reactivity
Human (predicted: Rat, Hamster, Cow, Xenopus laevis)
Applications
Flow Cyt, ICC/IF, IHC-P, WB
Target Information
Alternative Names
CTRCT30; Epididymis luminal protein 113; FLJ36605; HEL113; VIM; VIME_HUMAN; Vimentin
Function
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
Tissue Specificity
Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C. Avoid freeze / thaw cycle.
Storage Buffer
Tissue culture supernatant, Tris buffered saline, 1% BSA. pH: 7.50.
Preservative
0.1% Sodium Azide
