Product Size
5 mg
25 mg
Custom Size
Product Overview
Description
Competitive EGF receptor tyrosine kinase inhibitor.
Target
EGF receptor tyrosine kinase
Biological Description
Cell-permeable and competitive inhibitor of epidermal growth factor (EGF) receptor tyrosine kinase (IC50 = 3 μM). Effects platelet-derived growth factor (PDGF) and insulin receptor tyrosine kinases. Active in vivo.
Solubility Overview
Soluble in ethanol and in DMSO.
Chemical Properties
Chemical Name
2-[(3,4,5-Trihydroxyphenyl)methylidene]propanedinitrile
Molecular Weight (Da)
202.20
Molecular Formula
C10H6N2O3
SMILES
C1=C(C=C(C(=C1O)O)O)C=C(C#N)C#N
Storage & Handling
Storage Instructions
Store at room temperature. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
