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TSG101 Rabbit Polyclonal Antibody

Cat. No.: CLAB-00232372

Product Size: 20 µL 100 µL Custom Size

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Product Overview

Isotype
IgG
Reactivity
Human, Mouse (predicted: Rat)
Clonality
Polyclonal
Host Species
Rabbit
Conjugation
Unconjugated
Applications
WB

Target Information

Target Name
TSG101
UniProt No.
Q99816
Gene ID
7251
Alternative Names
ESCRT I complex subunit TSG101; ESCRT-I complex subunit TSG101; TS101_HUMAN; TSG 10; TSG 101; TSG10; Tsg101; Tumor susceptibility 101; Tumor susceptibility gene 10; Tumor susceptibility gene 101; Tumor susceptibility gene 101 protein; Tumor susceptibility protein; Tumor susceptibility protein isoform 3; VPS 23; VPS23
Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P--A-P. This interaction is essential for viral particle budding of numerous retroviruses.
Tissue Specificity
Heart, brain, placenta, lung, liver, skeletal, kidney and pancreas.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C long term. Avoid freeze / thaw cycle.
Storage Buffer
Tris citrate/phosphate, pH 7 to 8. pH: 7.
Preservative
0.09% Sodium Azide

For Research Use Only. Not For Clinical Use.

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