Product Size
50 mg
10 mg
Custom Size
Product Overview
Description
Topoisomerase inhibitor.
Alternative Names
SK&F 104864
Biological Description
Topoisomerase I inhibitor. Water-soluble derivative of camptothecin. Anticancer agent.
Solubility Overview
Soluble in water to 100 mM and in DMSO to 100 mM.
Chemical Properties
Chemical Name
(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride
Molecular Weight (Da)
457.91
Molecular Formula
C23H23N3O5.HCl
SMILES
Cl.CN(C)Cc1c2cc3CN4C(=O)C=5COC(=O)[C@](O)(CC)C=5C=C4c3nc2ccc1O
Storage & Handling
Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
