TBCD/SSD1 Mouse Polyclonal Antibody

Cat. No.: CLAB-00232332

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG
Reactivity
Human
Clonality
Polyclonal
Host Species
Mouse
Conjugation
Unconjugated
Applications
WB

Target Information

Target Name
TBCD
UniProt No.
Gene ID
Alternative Names
Beta tubulin cofactor D; Beta-tubulin cofactor D; KIAA0988; SSD 1; SSD-1; SSD1; tbcd; TBCD_HUMAN; tfcD; Tubulin folding cofactor D; Tubulin specific chaperone D; Tubulin-folding cofactor D; Tubulin-specific chaperone D
Function
Tubulin-folding protein; involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin. Acts as a GTPase-activating protein for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.
Tissue Specificity
Ubiquitously expressed.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Upon delivery aliquot and store at -20 °C or -80 °C. Avoid repeated freeze / thaw cycles.
Storage Buffer
PBS. pH: 7.4.

For Research Use Only. Not For Clinical Use.

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