SU4312, VEGFR and PDGFR Tyrosine Kinase Inhibitor

Cat. No.
CLIA-0130272
Product Size
5 mg 25 mg Custom Size

Product Overview

Description
Potent, selective VEGFR and PDGFR tyrosine kinase inhibitor.
Purity
> 98%
Form
Solid
Target
VEGFR and PDGFR tyrosine kinase
Biological Description
Potent, selective VEGFR and PDGFR tyrosine kinases inhibitor (IC50 values are 0.8 and 19.4 μM respectively). Shows anti-angiogenic effects. Active in vivo.
Source
Synthetic
CAS Number
5812-07-7
Solubility Overview
Soluble in DMSO to 75 mM.

Chemical Properties

Chemical Name
(3Z)-3-[[4-(Dimethylamino)phenyl]methylidene]-1H-indol-2-one
Molecular Weight (Da)
264.30
Molecular Formula
C17H16N2O
PubChem Identifier
SMILES
CN(C)C1=CC=C(C=C1)C=C2C3=CC=CC=C3NC2=O

Storage & Handling

Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

For Research Use Only. Not For Clinical Use.

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