STIL/SIL Rabbit Polyclonal Antibody

Cat. No.: CLAB-00232305

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG
Reactivity
Mouse, Rat
Clonality
Polyclonal
Host Species
Rabbit
Conjugation
Unconjugated
Applications
WB

Target Information

Target Name
STIL
UniProt No.
Gene ID
Alternative Names
DKFZp686O09161; MCPH7; OTTHUMP00000009566; SCL interrupting locus protein; SCL-interrupting locus protein; SCL/TAL1 interrupting locus; SIL; STIL; STIL_HUMAN; TAL 1 interrupting locus protein; TAL-1-interrupting locus protein
Function
Immediate-early gene. Plays an important role in embryonic development as well as in cellular growth and proliferation; its long-term silencing affects cell survival and cell cycle distribution as well as decreases CDK1 activity correlated with reduced phosphorylation of CDK1. Play a role as a positive regulator of the sonic hedgehog pathway, acting downstream of PTCH1.
Tissue Specificity
Expressed in all hematopoietic tissues and cell lines. Highly expressed in a variety of tumors characterized by increased mitotic activity with highest expression in lung cancer.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C or -80 °C. Avoid freeze / thaw cycle.
Storage Buffer
PBSBatches of this product that have a concentration < 1 mg/mL may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. pH: 7.40.
Preservative
0.02% Sodium Azide

For Research Use Only. Not For Clinical Use.

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