Product Size
1 x 96 tests
Custom Size
Product Information
Assay Type
Sandwich (quantitative)
Range
50 pg/mL-3200 pg/mL
Sample Type
Tissue Extracts, Cell Lysate
Detection Method
Colorimetric
Target Information
Alternative Names
BCD541; Component of gems 1; Gemin 1; Gemin-1; OTTHUMP00000125198; OTTHUMP00000223567; OTTHUMP00000223568; OTTHUMP00000224066; OTTHUMP00000226924; SMA; SMA 1; SMA 2; SMA 3; SMA 4; SMA@; SMA1; SMA2; SMA3; SMA4; SMN; SMN_HUMAN; SMN1; SMN2; SMNT; Survival motor neuron protein; Survival of motor neuron 1, telomeric; T-BCD541
Sequence Similarities
Belongs to the SMN family. Contains 1 Tudor domain.
Tissue Specificity
Expressed in a wide variety of tissues. Expressed at high levels in brain, kidney and liver, moderate levels in skeletal and cardiac muscle, and low levels in fibroblasts and lymphocytes. Also seen at high levels in spinal cord. Present in osteoclasts and mononuclear cells (at protein level).
Function
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage Instructions
Please refer to protocols.
