Product Overview
Reactivity
Human, Mouse, Rat, Porcine, Canine
Applications
IHC, WB, Peptide-ELISA
Target Information
Alternative Names
CCCAPAntigen NY-CO-8; Centrosomal colon cancer autoantigen protein; hCCCAP; NPHP10; NY-CO-8; serologically defined colon cancer antigen 8; SLSN7
Function
Plays a role in the establishment of cell polarity and epithelial lumen formation. Also plays an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis.
Tissue Specificity
Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Store at -20 °C. Avoid freeze-thaw cycles.
Storage Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA.
Preservative
0.02% Sodium Azide
