Product Size
10 mg
5 mg
Custom Size
Product Overview
Description
ALK inhibitor.
Biological Description
Potent and selective inhibitor of Activin Like Kinase. Inhibits ALK 4, 5 (IC50 = 94 nM), and 7. 3D Growth matrix component; also component of brain and blood vessel organoid differentiation media.
Solubility Overview
Soluble in DMSO to 100 mM and in ethanol to 10 mM.
Chemical Properties
Chemical Name
4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]benzamide
Molecular Weight (Da)
384.39
Molecular Formula
C22H16N4O3
SMILES
NC(=O)c1ccc(cc1)c3nc(c2ccccn2)c(n3)c4ccc5OCOc5c4
Storage & Handling
Storage Instructions
Store at room temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
