Product Size
1 x 96 tests
Custom Size
Product Information
Reactivity
Mouse, Rat, Human
Sample Type
Tissue Extracts
Assay Type
Sandwich (quantitative)
Range
0.31 ng/mL-
20 ng/mL
Detection Method
Colorimetric
Target Information
Function
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
Sequence Similarities
Belongs to the S-101 family. Contains 2 EF-hand domains.
Alternative Names
NEF; Protein S100 B; Protein S100-B; S 100 calcium binding protein beta chain; S 100 protein beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 protein beta chain; S100B; S100B_HUMAN; S100beta
Tissue Specificity
Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage Instructions
Store at 4 °C. Please refer to protocols.
