Product Size
25 mg
5 mg
Custom Size
Product Overview
Description
A GPX4 inhibitor and inducer of ferroptosis.
Biological Description
RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor and an inducer of ferroptosis. RSL3 increases lipid peroxidase levels in vitro and inhibits tumor formation and progression in vivo.
Solubility Overview
Soluble in DMSO to 35 mg/mL.
Chemical Properties
Chemical Name
methyl (1S,3R)-2-(2-chloroacetyl)-1-(4-methoxycarbonylphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxylate
Molecular Weight (Da)
440.90
Molecular Formula
C23H21ClN2O5
SMILES
COC(=O)C1CC2=C(C(N1C(=O)CCl)C3=CC=C(C=C3)C(=O)OC)NC4=CC=CC=C24
Storage & Handling
Storage Instructions
Shipped at 4 °C. Store at -20 °C long term. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
