Ro 3306, Cyclin-dependent Kinase (Cdk1) Inhibitor

Cat. No.
CLIA-0130104
Product Size
5 mg 1 mg Custom Size

Product Overview

Description
Selective cyclin-dependent kinase (CDK1) inhibitor.
Purity
> 99%
Form
Solid
Target
Cyclin-dependent kinase (CDK)
Biological Description
Selective cyclin-dependent kinase (Cdk1) inhibitor (Ki values are 35 and 110 nM for cdk1/cyclin B1 and cdk1/cyclin A, respectively). Enhances downstream p53 signaling. Induces G2/M-phase cell cycle arrest and apoptosis.
Source
Synthetic
CAS Number
872573-93-8
Solubility Overview
Soluble in DMSO to 100 mM.

Chemical Properties

Chemical Name
(5Z)-5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino)-4(5H)-thiazolone
Molecular Weight (Da)
351.44
Molecular Formula
C18H13N3OS2
PubChem Identifier
SMILES
C1=CC2=C(C=CC(=C2)/C=C\3/C(=O)N=C(S3)NCC4=CC=CS4)N=C1

Storage & Handling

Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

For Research Use Only. Not For Clinical Use.

Online Inquiry