Product Size
1 mg
10 mg
Custom Size
Product Overview
Description
Protein kinase inhibitor.
Biological Description
Widely used as a cell-permeable, reversible, competitive protein kinase C inhibitor. Also potently inhibits wide range of kinases inlcuding RSK1, RSK2, PRK2, PKD1, MSK1, GSK3β, CDK2-cyclin A and PIM3, as well as PKCα.
Solubility Overview
Soluble in DMSO and organic solvents. Solubility in these solvents is approximately 20 mg/mL.
Chemical Properties
Chemical Name
3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione methanesulfonate
Molecular Weight (Da)
553.65
Molecular Formula
C25H23N5O2S.CH3SO3H
SMILES
CS(=O)(=O)O.Cn2cc(c1ccccc12)C=5C(=O)NC(=O)C=5c4cn(CCCSC(=N)N)c3ccccc34
Storage & Handling
Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
