Recombinant TSG101 Rabbit Monoclonal Antibody

Cat. No.: CLAB-00232244

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host Species
Rabbit
Conjugation
Unconjugated
Applications
IP, WB
Clone Number
EPR7131(B)

Target Information

Target Name
TSG101
UniProt No.
Gene ID
Alternative Names
ESCRT I complex subunit TSG101; ESCRT-I complex subunit TSG101; TS101_HUMAN; TSG 10; TSG 101; TSG10; Tsg101; Tumor susceptibility 101; Tumor susceptibility gene 10; Tumor susceptibility gene 101; Tumor susceptibility gene 101 protein; Tumor susceptibility protein; Tumor susceptibility protein isoform 3; VPS 23; VPS23
Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P--A-P. This interaction is essential for viral particle budding of numerous retroviruses.
Tissue Specificity
Heart, brain, placenta, lung, liver, skeletal, kidney and pancreas.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C. Avoid freeze / thaw cycle. Stable for 12 months at -20 °C.
Storage Buffer
59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA. pH: 7.20.
Preservative
0.01% Sodium Azide

For Research Use Only. Not For Clinical Use.

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