Recombinant Tau (phospho S214) Rabbit Monoclonal Antibody

Cat. No.: CLAB-00232164

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG
Reactivity
Human, Mouse (predicted: Rat)
Clonality
Monoclonal
Host Species
Rabbit
Conjugation
Unconjugated
Applications
Dot blot, IHC-P, WB
Clone Number
EPR1884(2)

Target Information

Target Name
MAPT
UniProt No.
Gene ID
Alternative Names
AI413597; AW045860; DDPAC; FLJ31424; FTDP 17; G protein beta1/gamma2 subunit interacting factor 1; MAPT; MAPTL; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau; Microtubule associated protein tau isoform 4; Microtubule-associated protein tau; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament tau; Paired helical filament-tau; PHF tau; PHF-tau; PPND; PPP1R103; Protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; TAU; TAU_HUMAN; Tauopathy and respiratory failure; Tauopathy and respiratory failure, included
Function
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Tissue Specificity
Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C long term. Avoid freeze / thaw cycle.
Storage Buffer
59% PBS, 40% Glycerol (glycerin, glycerine), 0.5% BSA. pH: 7.2.
Preservative
0.01% Sodium Azide

For Research Use Only. Not For Clinical Use.

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