Recombinant STIL/SIL Rabbit Monoclonal Antibody - BSA and Azide Free (Detector)

Cat. No.: CLAB-00232152

Product Size: 20 µL 100 µL Custom Size

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Product Overview

Isotype

IgG

Reactivity

Human

Clonality

Monoclonal

Host Species

Rabbit

Conjugation

Unconjugated

Applications

Sandwich ELISA

Clone Number

EPR26955-50

Target Information

Target Name

STIL

UniProt No.

Q15468

Gene ID

6491

Alternative Names

DKFZp686O09161; MCPH7; OTTHUMP00000009566; SCL interrupting locus protein; SCL-interrupting locus protein; SCL/TAL1 interrupting locus; SIL; STIL; STIL_HUMAN; TAL 1 interrupting locus protein; TAL-1-interrupting locus protein

Function

Immediate-early gene. Plays an important role in embryonic development as well as in cellular growth and proliferation; its long-term silencing affects cell survival and cell cycle distribution as well as decreases CDK1 activity correlated with reduced phosphorylation of CDK1. Play a role as a positive regulator of the sonic hedgehog pathway, acting downstream of PTCH1.

Tissue Specificity

Expressed in all hematopoietic tissues and cell lines. Highly expressed in a variety of tumors characterized by increased mitotic activity with highest expression in lung cancer.

Shipping & Handling

Shipping

Shipped on dry ice.

Storage

Store at 4 °C.

Storage Buffer

100% PBS. pH: 7.20.

For Research Use Only. Not For Clinical Use.