Recombinant SIRT2 Rabbit Monoclonal Antibody

Cat. No.: CLAB-00232144

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG
Reactivity
Human
Clonality
Monoclonal
Host Species
Rabbit
Conjugation
Unconjugated
Applications
WB
Clone Number
EPR1667

Target Information

Target Name
SIRT2
UniProt No.
Gene ID
Alternative Names
FLJ35621; FLJ37491; NAD dependent deacetylase sirtuin 2; NAD dependent protein deacetylase sirtuin 2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; Silencing information regulator 2 like; Silent information regulator 2; SIR2; SIR2 like protein 2; Sir2 related protein type 2; SIR2, S. cerevisiae, homolog-loke 2; SIR2-like protein 2; SIR2L; SIR2L2; SIRT2; SIRT2_HUMAN; Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae); Sirtuin 2; Sirtuin type 2
Function
NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton.
Tissue Specificity
Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Store at -20 °C. Stable for 12 months at -20 °C.
Storage Buffer
9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant. pH: 7.2.
Preservative
0.01% Sodium Azide

For Research Use Only. Not For Clinical Use.

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