Recombinant Rat CERK Protein

Cat. No.: CLPP-00151341

Product Size: 10 µg Custom size

Product Overview

Description
CLPP-00151341 is recombinant rat CERK protein, Active
Applications
Functional Studies, SDS-PAGE
Protein Length
Full length protein
Animal Free
No
Nature
Recombinant Protein
Species
Rat
Form
Liquid
Sequence
MGAMGAAEPLQSVLWVKQQRCAVSLEPARALLRWWRSPEPGPSAPDPDAYSVPVSEIIAV
EEKEVHQKQSSNGRWHRMENPFAFTVHCVKRARHHRWKWARVTFWSADEQLCQLWLQTLR
ELLENLTSRPKHLLVFINPFGGKGQGKHIYEKKVAPLFTLASITTEIIITEHANQAKETL
YEINTDSYDGIVCVGGDGMFSEVLHGVIGKTQQSAGVDPNHPRAVLVPSTLRIGIIPAGS
TDCVCYSTVGTNDAETSALHIIIGDSLAIDVSSVHHNSTLLRYSVSLLGYGFYGDLIKDS
EKKRWMGLVRYDFSGLKAFLSHQYYEGTVSFLPAQHTVGSPRDQKPCRAGCSVCRQSKRQ
LEEEQKKALYGLENAEEVEEWQVVCGKFLAINSTNMSCACPRSPGGLSPFAHLGDGSSDL
ILIRKCSRFNFLRFLIRHTNQEDQFGFTFVEVYRVKKFQFTSKHVEDDDNDLKELEKQKF
GQICKDNPPCACPTSRSSWNCDGEVLHSPAIEVRVHCQLVRLFARGIEEES
Sequence Similarities
Contains 1 DAGKc domain.
Predicted Molecular Weight
61 kDa including tags
Tags
DDDDK tag C-Terminus

Target Information

Protein Name
CERK
UniProt No.
Alternative Names
Acylsphingosine kinase; Ceramide kinase; Cerk; CERK1_HUMAN; dA59H18.2; dA59H18.3; hCERK; KIAA1646; Lipid kinase 4; Lipid kinase LK4; LK4
Protein Function
Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Shows a greater preference for D-erythro isomer of ceramides. Binds phosphoinositides.
Tissue Specificity
High level expression in heart, brain, skeletal muscle, kidney and liver; moderate in peripheral blood leukocytes and thymus; very low in spleen, small intestine, placenta and lung.

Shipping & Handling

pH
pH: 8.0
Constituents
0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine)DDDDK peptide 100 ug/ml.
Shipping
Shipped on Dry Ice.
Storage
Store at -80 °C.

For Research Use Only. Not For Clinical Use.

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