Product Overview
Applications
Flow Cyt (Intra), ICC/IF, IHC-P, IP
Target Information
Alternative Names
Centrosome Marker; Ken; Kendrin; KIAA0402; MOPD2; PCN; PCNT 2; PCNT; PCNT B; PCNT_HUMAN; PCNT1; PCNT2; PCNTB; PCTN2; Pericentrin 1; Pericentrin 2; Pericentrin 380; Pericentrin; Pericentrin B; Pericentrin-B; SCKL4
Function
Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material. May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome.
Tissue Specificity
Expressed in all tissues tested, including placenta, liver, kidney and thymus.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Store at 4 °C. Do Not Freeze.
Storage Buffer
PBS. pH: 7.2.
