Product Overview
Reactivity
Human, Mouse, Rat
Applications
Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB
Target Information
Alternative Names
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; PCNA; Pcna/cyclin; PCNA_HUMAN; PCNAR; Polymerase delta accessory protein; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03
Function
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C. Stable for 12 months at -20 °C.
Storage Buffer
59% PBS, 40% Glycerol, 0.05% BSA. pH: 7.20.
Preservative
0.01% Sodium Azide
