Product Overview
Reactivity
Human (predicted: Mouse, Rat)
Applications
Flow Cyt (Intra), WB
Target Information
Alternative Names
50 kD dynein associated polypeptide; 50 kDa dynein associated polypeptide; 50 kDa dynein-associated polypeptide; DCTN-50; DCTN2; DCTN2_HUMAN; DCTN50; dynactin 2 (p50); dynactin 2; dynactin complex 50 kD subunit; Dynactin complex 50 kDa subunit; Dynactin subunit 2; DYNAMITIN; p50 dynamitin; RBP50
Function
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Store at -20 °C. Stable for 12 months at -20 °C.
Storage Buffer
0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant. pH: 7.20.
Preservative
0.05% Sodium Azide