Product Overview
Applications
Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB
Reactivity
Human, Mouse, Rat
Target Information
Alternative Names
Cellular myosin heavy chain; Cellular myosin heavy chain type B; Cellular myosin heavy chain type B type B; MGC134913; MGC134914; MYH 10; Myh10; MYH10_HUMAN; Myosin 10; Myosin heavy chain 10; Myosin heavy chain 10 non muscle; Myosin heavy chain; Myosin heavy chain non muscle 11b; Myosin heavy chain nonmuscle IIb; Myosin heavy chain nonmuscle type B; Myosin heavy polypeptide 10 non muscle; Myosin-10; Myosin10; NMMHC B; NMMHC II b; NMMHC II-b; NMMHC IIB; NMMHC-B; NMMHC-IIB; NMMHCB; Non muscle myosin heavy chain B; Non muscle myosin heavy chain IIB; Non muscle myosin II heavy chain B; non-muscle IIb; Non-muscle myosin heavy chain B; Non-muscle myosin heavy chain IIb; Nonmuscle myosin heavy chain B; Nonmuscle myosin heavy chain IIB; Nonmuscle myosin II heavy chain B; Nonmuscle myosin IIB; type B
Tissue Specificity
Isoform 1 is expressed in cerebellum and spinal chord. Isoform 2 is expressed in cerebrum and retina. Isoform 3 is expressed in the cerebrum and to a much lower extent in cerebellum.
Function
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C long term. Avoid freeze / thaw cycle.
Storage Buffer
PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA. pH: 7.2.
Preservative
0.01% Sodium Azide