Product Overview
Reactivity
Human, Mouse, Rat
Applications
Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB
Target Information
Alternative Names
ac4 °C enzyme; ac4 °C writer; DKFZp434 °C116; FLJ10774; FLJ12179; FLJ23850; hALP; KIAA1709; N acetyltransferase 10; N acetyltransferase 10 GCN5 related; N acetyltransferase like; N acetyltransferase like protein; N-acetyltransferase 10; NAT10; NAT10_HUMAN; NET43
Function
Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C long term. Avoid freeze / thaw cycle.
Storage Buffer
59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA. pH: 7.2.
Preservative
0.01% Sodium Azide
