Recombinant Mouse Thrombopoietin Protein

Cat. No.: CLPP-00151333

Product Size: 100 µg Custom size

Product Overview

Description
CLPP-00151333 is recombinant mouse THPO protein
Purity
> 95%
Applications
SDS-PAGE
Protein Length
Full length protein
Animal Free
Yes
Nature
Recombinant Protein
Species
Mouse
Endotoxin Level
< 0.005 Eu/µg
Form
Lyophilized
Sequence
SPVAPACDPRLLNKLLRDSHLLHSRLSQCPDVDPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPLQGRTTAHKDPNALFLSLQQLLRGKVRFLLLVEGPTLCVRRTLPTTAVPSSTSQLLTLNKFPNRTSGLLETNFSVTARTAGPGLLSRLQGFRVKITPGQLNQTSRSPVQISGYLNRTHGPVNGTHGLFAGTSLQTLEASDISPGAFNKGSLAFNLQGGLPPSPSLAPDGHTPFPPSPALPTTHGSPPQLHPLFPDPSTTMPNSTAPHPVTMYPHPRNLSQET
Sequence Similarities
Belongs to the EPO/TPO family.
Predicted Molecular Weight
36 kDa

Target Information

Protein Name
THPO
UniProt No.
Alternative Names
C mpl ligand; C-mpl ligand; Megakaryocyte colony stimulating factor; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; Megakaryocyte stimulating factor; MGC163194; MGDF; MKCSF; ML; MPL ligand; MPLLG; Myeloproliferative leukemia virus oncogene ligand; Prepro thrombopoietin; THCYT1; THPO; Thrombopoietin; Thrombopoietin nirs variant 1; TPO; TPO_HUMAN
Protein Function
Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Involvement in Disease
Defects in THPO are a cause of essential thrombocythemia (ET). ET is inherited as an autosomal dominant trait which is characterized by elevated platelet levels due to sustained proliferation of megakaryocytes, and frequently lead to thrombotic and haemorrhagic complications.

Shipping & Handling

Constituents
0.727% Dibasic monohydrogen potassium phosphate, 0.248% Monobasic dihydrogen potassium phosphate, 10.26% Trehalose.
Shipping
Shipped at Room Temperature.
Storage
Store at room temperature.

For Research Use Only. Not For Clinical Use.

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