Recombinant Mouse OSTM1 Protein

Cat. No.: CLPP-00151323

Product Size: 100 µg Custom size

Product Overview

Description
CLPP-00151323 is recombinant mouse OSTM1 protein, His tag
Purity
> 95%
Applications
SDS-PAGE
Protein Length
Protein fragment
Animal Free
No
Nature
Recombinant Protein
Species
Mouse
Endotoxin Level
< 1.000 Eu/µg
Form
Lyophilized
Sequence
MARDAELARSSGWPWRWLPALLLLQLLRWRCALCALPFTSSRHPGFADLLSEQQLLEVQDLTLSLLQGGGLGPLSLLPPDLPDLEPECRELLMDFANSSAELTACMVRSARPVRLCQTCYPLFQQVAIKMDNISRNIGNTSEGPRCGGSLLTADRMQIVLMVSEFFNSTWQEANCANCLTNNGEDLSNNTEDFLSLFNKTLACFEHNLQGHTYSLLPPKNYSEVCRNCKEAYKNLSLLYSQMQKLNGLENKAEPETHLCIDVEDAMNITRKLWSRTFNCSVTCSDTVS
Predicted Molecular Weight
30 kDa including tags
Tags
His tag C-Terminus

Target Information

Protein Name
OSTM1
UniProt No.
Alternative Names
Chloride channel 7 beta subunit; GAIP-interacting protein N terminus; GIPN; GL; Grey lethal osteopetrosis; HSPC019; OPTB5; Osteopetrosis-associated transmembrane protein 1; Ostm1; OSTM1_HUMAN; OTTHUMP00000016938; OTTHUMP00000196342
Protein Function
Required for osteoclast and melanocyte maturation and function.
Involvement in Disease
Defects in OSTM1 are the cause of osteopetrosis autosomal recessive type 5 (OPTB5); also called infantile malignant osteopetrosis 3. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. OPTB5 patients manifest primary central nervous system involvement in addition to the classical stigmata of severe bone sclerosis, growth failure, anemia, thrombocytopenia and visual impairment with optic atrophy.

Shipping & Handling

pH
pH: 7.4
Constituents
100% PBS.
Shipping
Shipped at Room Temperature.
Storage
Store at -20 °C or -80 °C.

For Research Use Only. Not For Clinical Use.

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