Recombinant Mouse NPP-7 Protein

Cat. No.: CLPP-00151322

Product Size: 20 µg Custom size

Product Overview

Description
CLPP-00151322 is recombinant mouse ENPP7 protein, His tag
Purity
> 90%
Applications
SDS-PAGE
Protein Length
Protein fragment
Animal Free
No
Nature
Recombinant Protein
Species
Mouse
Endotoxin Level
< 1.000 Eu/µg
Form
Lyophilized
Sequence
MGHSAVLLCVALAILPACVTGAPVQRQHKLLLVSFDGFRWNYDQDVDTPNLDSMAQEGVKAQYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMFYNTTSTVRLPYHATLGIQRWWDNGSIPIWITAQRQGLKTGSFFYPGGNVTYQGEAVTMSRKEGVLHNYKNETEWRGNVDTVMKWFLEEDVSLVTLYFGEPDSTGHKYGPESQERKDMVKQVDRTVGYLRDSIKRHHLSDSLNLIITSDHGMTTVNKKASDLVEFHKFSNFTFQDIQFELLDYGPIGMLIPKEGMLEKVYSVLKDAHPRLHVYKKEDFPKNFHYANNPRITPLLMYSDLGYVIHGRVNVQFNNGEHGFNNQDMDMKTIFRAVGPSFKAGLEVEPFESVHVYELMCQLLGIVPEPNDGNPGILRPMLRSGSASLLSSQ
Sequence Similarities
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
Predicted Molecular Weight
47 kDa including tags
Tags
His tag C-Terminus

Target Information

Protein Name
ENPP7
UniProt No.
Alternative Names
ALK SMase; Alk-SMase; Alkaline sphingomyelin phosphodiesterase; E-NPP 7; Ectonucleotide pyrophosphatase/phosphodiesterase 7; Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; ENPP7; ENPP7_HUMAN; Intestinal alkaline sphingomyelinase; NPP-7
Protein Function
Choline-specific phosphodiesterase that hydrolyzes sphingomyelin releasing the ceramide and phosphocholine and therefore is involved in sphingomyelin digestion, ceramide formation, and fatty acid (FA) absorption in the gastrointestinal tract. Has also phospholipase C activity and can also cleave phosphocholine from palmitoyl lyso-phosphatidylcholine and platelet-activating factor (PAF) leading to its inactivation. Does not have nucleotide pyrophosphatase activity. May promote cholesterol absorption by affecting the levels of sphingomyelin derived from either diet or endogenous sources, in the intestinal lumen (By similarity).
Tissue Specificity
Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon.

Shipping & Handling

pH
pH: 7.6
Constituents
0.24% Tris, 0.87% Sodium chloride.
Shipping
Shipped at Room Temperature.
Storage
Store at -20 °C or -80 °C.

For Research Use Only. Not For Clinical Use.

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