Product Overview
Description
CLPP-00151262 is recombinant human VAV1 protein
Applications
Mass Spectrometry, SDS-PAGE
Protein Length
Protein fragment
Nature
Recombinant Protein
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFLKPLQRFLKPQDIEIIFINIEDLLRVHTHFLKEMK
EALGTPGAANLYQVFIKYKERFLVYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICK
RRGDSYDLKDFVNLHSFQVRDDSSGDRDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRASAHKECLGRVPPCG
Sequence Similarities
Contains 1 CH (calponin-homology) domain. Contains 1 DH (DBL-homology) domain. Contains 1 PH domain. Contains 1 phorbol-ester/DAG-type zinc finger. Contains 1 SH2 domain. Contains 2 SH3 domains.
Predicted Molecular Weight
47 kDa including tags
Target Information
Alternative Names
Oncogene vav; p95Vav; Proto-oncogene vav; Protooncogene vav; VAV; VAV 1; VAV 1 oncogene; Vav proto oncogene; VAV_HUMAN; VAV1
Protein Function
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Tissue Specificity
Widely expressed in hematopoietic cells but not in other cell types.
Shipping & Handling
Constituents
0.32% Tris-HCl buffer, 1.17% Sodium chloride, 30% Glycerol (glycerin, glycerine), 0.03% DTT.
Shipping
Shipped at 4 °C.
Storage
Store at -20 °C or -80 °C.
