Recombinant Human Troponin I2 Fast Skeletal Muscle Protein

Cat. No.: CLPP-00151237

Product Size: 20 µg Custom size

Product Overview

Description
CLPP-00151237 is recombinant human TNNI2 protein, denatured
Purity
> 90%
Applications
SDS-PAGE
Protein Length
Full length protein
Animal Free
No
Nature
Recombinant Protein
Species
Human
Form
Liquid
Sequence
MGSSHHHHHHSSGLVPRGSHMGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESES
Predicted Molecular Weight
24 kDa including tags
Sequence Similarities
Belongs to the troponin I family.
Tags
His tag N-Terminus

Target Information

Protein Name
TNNI2
Alternative Names
AMCD 2B; AMCD2B; DA 2B; DA2B; fast skeletal muscle; Fast twitch skeletal muscle troponin I; fast-twitch isoform; FSSV; fsTnI; TNNI 2; Tnni2; TNNI2_HUMAN; tro; Troponin I; Troponin I fast skeletal muscle; Troponin I fast twitch 2; Troponin I fast twitch isoform; Troponin I fast twitch skeletal muscle isoform; Troponin I skeletal fast; Troponin I type 2; Troponin I type 2 (skeletal fast)
Protein Function
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
UniProt No.
Involvement in Disease
Defects in TNNI2 are a cause of distal arthrogryposis type 2B (DA2B); also known as arthrogryposis multiplex congenita, distal, type 2B (AMCD2B). DA2B is a form of inherited multiple congenital contractures. Affected individuals have vertical talus, ulnar deviation in the hands, severe camptodactyly, and a distinctive face characterized by a triangular shape, prominent nasolabial folds, small mouth and a prominent chin.

Shipping & Handling

Shipping
Shipped at 4 °C.
Storage
Store at -20 °C or -80 °C.
Constituents
12.01% Urea, 0.32% Tris HCl, 20% Glycerol (glycerin, glycerine), 1.17% Sodium chloride.
pH
pH: 8.0

For Research Use Only. Not For Clinical Use.

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