Product Overview
Description
CLPP-00151142 is recombinant human PLS3 protein
Protein Length
Full length protein
Nature
Recombinant Protein
Sequence
MASMTGGQQMGRGHHHHHHENLYFQGGEFDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV
Sequence Similarities
Contains 2 actin-binding domains. Contains 4 CH (calponin-homology) domains. Contains 2 EF-hand domains.
Predicted Molecular Weight
74 kDa including tags
Tags
His-T7 tag N-Terminus
Target Information
Alternative Names
BMND18; Plastin 3; Plastin 3 (T isoform); Plastin-3; PLS3; PLST_HUMAN; T fimbrin; T-plastin
Protein Function
Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia.
Tissue Specificity
Expressed in a variety of organs, including muscle, brain, uterus and esophagus.
Involvement in Disease
Osteoporosis (OSTEOP): A systemic skeletal disorder characterized by decreased bone mass and deterioration of bone microarchitecture without alteration in the composition of bone. The result is fragile bones and an increased risk of fractures, even after minimal trauma. Osteoporosis is a chronic condition of multifactorial etiology and is usually clinically silent until a fracture occurs. Disease susceptibility is associated with variants affecting the gene represented in this entry.
Shipping & Handling
Constituents
0.32% Tris HClContains NaCl, KCl, EDTA, sucrose, and DTT.
Shipping
Shipped at 4 °C.
