Recombinant Human SIRT2 Protein

Cat. No.: CLPP-00151112

Product Size: 100 µg Custom size

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Product Overview

Description

Recombinant human SIRT2 protein

Purity

> 95%

Applications

HPLC, Mass Spectrometry, SDS-PAGE

Protein Length

Full length protein

Animal Free

Yes

Nature

Recombinant Protein

Species

Human

Endotoxin Level

< 0.005 Eu/µg

Form

Lyophilized

Sequence

AEPDPSHPLETQAGKVQEAQDSDSDSEGGAAGGEADMDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ

Sequence Similarities

Belongs to the sirtuin family. Contains 1 deacetylase sirtuin-type domain.

Predicted Molecular Weight

43 kDa

Actual Molecular Weight

43 kDa

Target Information

Protein Name

SIRT2

UniProt No.

Q8IXJ6

Alternative Names

FLJ35621; FLJ37491; NAD dependent deacetylase sirtuin 2; NAD dependent protein deacetylase sirtuin 2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; Silencing information regulator 2 like; Silent information regulator 2; SIR2; SIR2 like protein 2; Sir2 related protein type 2; SIR2, S. cerevisiae, homolog-loke 2; SIR2-like protein 2; SIR2L; SIR2L2; SIRT2; SIRT2_HUMAN; Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae); Sirtuin 2; Sirtuin type 2

Protein Function

NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton.

Tissue Specificity

Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network.

Shipping & Handling

Constituents

0.727% Dibasic monohydrogen potassium phosphate, 0.248% Monobasic dihydrogen potassium phosphate, 10.26% Trehalose.

Shipping

Shipped at Room Temperature.

Storage

Store at room temperature.

For Research Use Only. Not For Clinical Use.