Recombinant Human SDCCAG8 Protein

Cat. No.: CLPP-00151088

Product Size: 10 µg Custom size

Product Overview

Description
CLPP-00151088 is recombinant human SDCCAG8 protein
Applications
ELISA, SDS-PAGE, Western Blot
Protein Length
Full length protein
Animal Free
No
Nature
Recombinant Protein
Species
Human
Form
Liquid
Sequence
MAKSPENSTLEEILGQYQRSLREHASRSIHQLTCALKEGDVTIGEDAPNLSFSTSVGNEDARTAWPELQQSHAVNQLKDLLRQQADKESEVSPSRRRKMSPLRSLEHEETNMPTMHDLVHTINDQSQYIHHLEAEVKFCKEELSGMKNKIQVVVLENEGLQQQLKSQRQEETLREQTLLDASGNMHNSWITTGEDSGVGETSKRPFSHDNADFGKAASAGEQLELEKLKLTYEEKCEIEESQLKFLRNDLAEYQRTCEDLKEQLKHKEFLLAANTCNRVGGLCLKCAQHEAVLSQTHTNVHMQTIERLVKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKHPSQ
Predicted Molecular Weight
67 kDa including tags

Target Information

Protein Name
SDCCAG8
UniProt No.
Alternative Names
Antigen NY CO 8; Antigen NY-CO-8; BBS16; CCCAP; CCCAP SLSN7; Centrosomal colon cancer autoantigen protein; hCCCAP; HSPC085; NPHP10; NPHP10 gene; NY-CO-8; Sdccag8; SDCG8_HUMAN; Serologically defined colon cancer antigen 8; Serologically defined colon cancer antigen 8 homolog; SLSN7; SLSN7 gene
Protein Function
Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). Also plays an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis.
Tissue Specificity
Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.
Involvement in Disease
Senior-Loken syndrome 7 (SLSN7): A renal-retinal disorder characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes apparent during the first year of life. The disease is caused by mutations affecting the gene represented in this entry.

Shipping & Handling

pH
pH: 8.0
Constituents
0.31% Glutathione, 0.79% Tris HCl.
Shipping
Shipped on dry ice.
Storage
Store at -80 °C.

For Research Use Only. Not For Clinical Use.

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