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Recombinant Human PTPN13/FAP1 Protein

Cat. No.: CLPP-00151025

Product Size: 5 µg Custom size

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Product Overview

Description
CLPP-00151025 is recombinant human PTPN13/FAP-1 protein, Active
Purity
> 90%
Applications
Functional Studies, SDS-PAGE
Protein Length
Protein fragment
Animal Free
No
Nature
Recombinant Protein
Species
Human
Form
Liquid
Sequence
DHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK
Tags
GST tag N-Terminus

Target Information

Protein Name
PTPN13
Alternative Names
APO1/CD95 (Fas) associated phosphatase; DKFZp686J1497; FAP 1; FAP1; Fas associated phosphatase 1; Fas associated protein tyrosine phosphatase 1; HGNC:9646; hPTPE1; Phosphatase rip; PNP 1; PNP1; Protein tyrosine phosphatase 1 Fas associated; protein tyrosine phosphatase 1E; Protein tyrosine phosphatase non receptor type 13; Protein tyrosine phosphatase nonreceptor type 13; Protein tyrosine phosphatase PTPL1; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase); PTP BAS; PTP BL; PTP E1; PTP1E; PTPL 1; PTPL1; PTPLE; PTPN 13; PTPN13; Tyrosine protein phosphatase non receptor type 13
Protein Function
PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as I-kappa-B-alpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway.

Shipping & Handling

pH
pH: 7.5
Constituents
0.42% MOPS, 0.29% Sodium chloride, 0.31% Glutathione, 0.004% DTT, 0.002% PMSF, 30% Glycerol (glycerin, glycerine).
Shipping
Shipped on Dry Ice.
Storage
Store at -80 °C.

For Research Use Only. Not For Clinical Use.

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