Product Overview
Description
CLPP-00151011 is recombinant human PFN2 protein
Applications
HPLC, SDS-PAGE
Protein Length
Full length protein
Nature
Recombinant Protein
Endotoxin Level
< 1.000 Eu/µg
Sequence
MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFFTNGLALGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF
Sequence Similarities
Belongs to the profilin family.
Predicted Molecular Weight
15 kDa
Target Information
Alternative Names
D3S1319E; PFL; PFN 2; Pfn2; PROF2_HUMAN; Profilin II; Profilin-2; Profilin2; ProfilinII
Protein Function
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Tissue Specificity
Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
Shipping & Handling
Constituents
0.24% Tris, 0.88% Sodium chloride.
Shipping
Shipped at 4 °C.
Storage
Store at -20 °C for long term.
