Product Overview
Description
CLPP-00150992 is recombinant human PKP1 protein
Protein Length
Protein fragment
Nature
Recombinant Protein
Sequence
MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLRNFTSRF
Sequence Similarities
Belongs to the beta-catenin family. Contains 9 ARM repeats.
Predicted Molecular Weight
29 kDa
Tags
His-DHFR tag N-Terminus
Target Information
Alternative Names
B6P; Band 6 protein; PKP1; PKP1_HUMAN; Plakophilin 1 (ectodermal dysplasia/skin fragility syndrome); Plakophilin-1
Protein Function
Seems to play a role in junctional plaques. Contributes to epidermal morphogenesis.
Tissue Specificity
Isoform 2 is widely expressed. Isoform 1 is expressed in stratified squamous, complex, glandular duct and bladder epithelia.
Involvement in Disease
Ectodermal dysplasia-skin fragility syndrome.
Shipping & Handling
Constituents
0.32% Tris HCl, 0.58% Sodium chloride.
Shipping
Shipped at 4 °C.
