Product Overview
Description
CLPP-00150935 is recombinant human RPRD1A protein
Applications
Mass Spectrometry, SDS-PAGE
Protein Length
Full length protein
Nature
Recombinant Protein
Sequence
MGSSHHHHHHSSGLVPRGSHMGSEFMSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLAND
VIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENENCSSLG
SPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLA
DFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHLPFAGDIYSED
Sequence Similarities
Belongs to the UPF0400 (RTT103) family. Contains 1 CID domain.
Predicted Molecular Weight
38 kDa including tags
Target Information
Alternative Names
C77387; CDKN2B-related protein; Cyclin dependent kinase 2B inhibitor related protein; Cyclin dependent kinase inhibitor 2B related protein; Cyclin dependent kinase inhibitor 2B related protein (p15INK4B related protein); Cyclin dependent kinase inhibitor related protein; Cyclin-dependent kinase inhibitor 2B-related protein; FLJ10656; HsT3101; Hypothetical protein FLJ10656; KIAA4077; MGC19513; MGC29396; MGC36325; mKIAA4077; p15INK4B related protein; p15INK4B-related protein; Putative uncharacterized protein P15RS; Regulation of nuclear pre mRNA domain containing 1A; Regulation of nuclear pre-mRNA domain-containing protein 1A; RGD1307374; RPR1A_HUMAN; RPRD1A
Protein Function
Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
Shipping & Handling
Constituents
0.32% Tris HCl, 20% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.02% DTT.
Shipping
Shipped at 4 °C.
Storage
Store at -20 °C or -80 °C.
